New neon http driver not working with pooled connections

is the new { drizzle } from "drizzle-orm/neon-http" not compatible with pooled connections? Getting error when I do:
const pool = new Pool({ connectionString: env.DATABASE_URL });
export const db = drizzle(pool);

but works when
const pool = neon(env.DATABASE_URL);
export const db = drizzle(pool);
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