FlowLayoutPanel TopDown problem

Panel panel = new Panel()
{
    Size = new Size(643, 362),//643, 426),
    Location = new Point(0, 0),
    BackColor = Color.Transparent, 
    Name = "Q",
    Dock = DockStyle.Fill
};

FlowLayoutPanel q = new FlowLayoutPanel()
{
    Size = new Size(633, 352), //392),
    Location = new Point(10, 10),
    BackColor = Color.Transparent, //Color.FromArgb(63, 98, 227),
    Anchor = AnchorStyles.Top | AnchorStyles.Right | AnchorStyles.Bottom | AnchorStyles.Left,
    FlowDirection = FlowDirection.TopDown,
    AutoScroll = true,
    AllowDrop = true,
    WrapContents = false,
    AutoSizeMode = AutoSizeMode.GrowAndShrink,
};

q.VerticalScroll.Visible = true;

Thematic thematic = Database.db.RetrieveThematicInfo(Database.db.GetThematicId(thematicName));

foreach (var theme in thematic.Themes)
{
    Panel qPanel = new Panel()
    {
        Size = new Size(q.ClientSize.Width - 20, 45),
        BackColor = Color.FromArgb(63, 98, 227),
        Anchor = AnchorStyles.Left | AnchorStyles.Right,
        Margin = new Padding(0, 0, 0, 10),
    };

    Label themelabel = new Label()
    {
        Text = theme.Name,
        Location = new Point(13, 12),
        TextAlign = ContentAlignment.MiddleCenter,
        Font = new Font("Arial Rounded MT Bold", 13),
        Anchor = AnchorStyles.Left,
        AutoEllipsis = true,
        AutoSize = true,
        ForeColor = Color.FromArgb(225, 226, 208)
    };
    
    MaterialButton start = new MaterialButton()
    {
        Text = "START",
        Cursor = Cursors.Hand,
        Location = new Point(qPanel.Width - 100, 5),
        ForeColor = Color.FromArgb(225, 226, 208),
        BackColor = Color.FromArgb(115, 133, 222),
        Anchor = AnchorStyles.Right
    };

    qPanel.Controls.Add(themelabel);
    qPanel.Controls.Add(start);
    q.Controls.Add(qPanel);
}