Accessing .dev.vars outside of context

APPWRITE_ENDPOINT=
APPWRITE_PROJECT_ID=
APPWRITE_API_KEY=

import { Hono } from "hono";
import { Users, Account } from 'node-appwrite';

const app = new Hono();

const client = new Client()
  .setEndpoint("") // I want to use APPWRITE_ENDPOINT here
  .setProject("")  // And APPWRITE_PROJECT_ID here
  .setKey("");     // And APPWRITE_API_KEY here

app.get("/users", (c) => {
  const users = new Users(client);
  ....
});

app.get("/create", (c) => {
  const account = new Account(client);
  account.create();
  .....
});

export default app;