Is it possible to render a route within a routes <Outlet />?

I have an inbox component, on the left side i have a list of notifications wich is inside a layout. And then on the right side there is a <Outlet /> component.

Clicking on one of the notifications should ideally take me to a /issue/id page - but instead of doing that, can i instead render that /issue/id page on the right side of my layout where the <Outlet/> component is?

Thanks for help.