Belt slipping or stepper blocking?

I have a weird problem with my printer. I've had quite the rough ride with the upgrade to vCore 3.1 but managed to get it working. I've printed a bunch of files (PLA) and all seems well in paradise.

However - what happens now is the following. At random moments during a print (or sometimes even during the initial mesh) it sounds like one of the steppers just blocks and the X-Y messes up. It basically shifts a few steps to one side, resulting in failed prints (the center is no longer the center). Sometimes it happens during the mesh but sometimes it happens after printing a bunch of layers.

I've checked the grub screws, looked at belt tension, even double-checked the wiring - but I'm baffled. Anyone have an idea of what might be going on?
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