Strage extrusion and z-offset behaviour

Hi, I have a v-minion. Always printing good. But from some time I having problems with the z-offset and the extrusion. Both my slicers (Cura and SuSl) are setted to relative extrusion like in RatOs variable. My z-offset is correctly calibrated. But randomly, from print to print, I get irregular extrusion or incorrect z-offset (or too low or too high). Sometimes reboot the firmware is the only solution to fix it. Any ideas?
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