How do I use NOW() in Drizzle?

Can someone explain how to write the following query in Drizzle?

UPDATE users
SET datetime_last_login = NOW()
WHERE id = $1

UPDATE users
SET datetime_last_login = NOW()
WHERE id = $1

UPDATE users
SET datetime_last_login = NOW()
WHERE id = $1

UPDATE users
SET datetime_last_login = NOW()
WHERE id = $1