Loop Optimization

anyone have any good resources for learning about loop Optimization in c#?

I am making really good logical changes to my code by taking out if statements and removing other reoccurring code that doesn't need to be called all the time and i am actually somehow increasing the amount of time it takes my loop to run ...

it makes absolutely no sense .. so i want to start studying this subject to have a better understanding of what the hell is going on
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