99 Replies
@Sheldon J. Plankton
Note for OP
+solved @user1 @user2... to close the thread when your doubt is solved. Mention the users who helped you solve the doubt. This will be added to their stats.,rotate
affected female with unaffected father isnt possible in x linked recessive
an ans key error perhaps
arihant...
I'll try this ruko
Actually kayi baar multiple types match kar rahe hote hain
And we have to choose the most probable
yeah.. like jabhi x linked hai it can be opened by autosomal too
Hmm hmm
You gotta use some factors to rule the other out
Mai ek kaam kar raha tha bas kuch
Will se ek min me
hnn
that i did
y linked to hoga nhi
yes thats male to male inheritance
holandric genes
x linked me dominant agar hota to puri progeny hoti (if mother is hetero)
lekin agar vo hota to phir daughter ki next gen me nhi jata
i feel like it can be x linked dominant
x' here is affected
progeny ke chnces ke hisab se socho
aise to maine bhi first me yahi socha tha
na that doesn't matter
probability ek large sampling size me dekhte hai
bhyi matar nhi human hai 💀
but still
just cuz the probability of having a female child is 1/2 doesnt mean u have to always have one boy and one girl
likewise
ik
par dekho 3 male hai 2 affected hai
2 daughter hai
dono affected hai
in general when we get asked qs like this in our tests, we usually have multiple correct options
cuz x linked can also be possible.. probability toh matlab population ki baat hai
hnn
that ik
but yeah we can say that autosomal dominant may be the more appropriate opt
thats what i am saying
yeah sry
that makes sense
all im saying tho is that we dont really look at probability to rule em out
may help with precision
i mean hame bole hai sir ki best probable
😭
im not disregaring just
yaar best to vahi hona haina
yeah
that's right
Okay
Now I’m here
Hey what does which colour represent @Sephrina
Maine black and white me hi kiya hai ye
pink is affected
blue isnt affected
vaise given nhi hai
par red ke hisab se hota hai
to that i am assuming
Kahin usi ki vajah se na dikkat ho
yeah that thing just came to my mind...
par still x linked nhi hota to ..
I notice a pattern
Females are more affected than males
hnn
they are
That points towards X linked I suppose
F1 me bhi and f2 me bhi
Dominant nahi hai btw autosomal
not so sure about this
Tumhara kaise aaya I didn’t get it
kyu?
exactly... cuz x linked he toh males have more chance of being affected.. esp if it's recessive
hn
kyunki male me just would need one altered x
Autosomal dominant agar hua to parentals me pure lines honge
Fir F1 would be affected completely
Which is not the case
balki female me agar reccesive hai to 2
pure line?
AA aa
hn vo mai smj gyi
Gives all Aa
why pure lines, could be heterozygous
dominant hetero bhi hota hai
...
Accha haan
Sorry
I think so it can also be done by the statement that mitochondria is the power house of the cell
Aa bhi ho sakti haina mother
Hmm hmm
dekho mai bhaga dungi
meri thread na khrb karo 😭
Autosomal recessive bhi baith gaya mera to
I am telling till my extent of bio knowledge I will leave
My bad
dikhao
stay on topic please.
bhyi....
ik baat bato
ki agar meri cross kar rhi hai to there is 50% chnce na
mai kaise assume karlu ki dono me vahi hona
Independent events hain ji
yup.. basically autosomal and x linked dominant as well as autosomal rec works here..
ofc
par still im talking about chance
To ye bhi possibility to hai na
Statistically socho
most probs to nhi hona
Hamara sample size chhota hai bohot
vahi to mai bolri
To iske bhi acche khaase chances hain
Idk upar ka lol
Are but hamara sample size chhota hai na
Ab agar 6 times coin toss kiya agar
To jaruri thodi hai 3 times heads aayega
Hmm hmm
So now
I feel like ‘cause females are affected more
I’m tending towards X linked
i dont think so
ki agar female more hai to x ke chance honge jyda
Usme bhi issue hai I get it
aree ik that
par ye assume ideal situations
ki hamare jo bhi punnet se aara vahi hona
Naah aise nahi hota ji
Pedigree me le sakte hain baaki possibilities
waah kaise nhi hota
humko bataye hai
ki best ans ke liye assume ideal
le sakte hai
that i agree par to check hume dekhna pehle ideal hota hai
Maybe idk then
Mai koi accha reason soch raha hun
To rule out others
Kyunki satisfy to saare ho jayenge I guess
X linked dominant ho raha hai satisfy kya?
na
Then yaar X linked recessive hi hona
dominant hota to puri progeny ko hona padta affected varna jo daughter hai uske 2 daughters nhi hoti affected
Kyunki autosomal ke hisab se isme bias bohot hain
this is by x linked dominant
Females literally double affected hain
Ho raha na matlab satisfy
Vo sense bhi bana raha hai ngl
yeah so it's all of em except x linked rec
again vahi baat ki probablity
X linked recessive nahi ho raha?
merko vo chiz nhi smj aari
ki agar probablity ke hisab se dekhe to ye kaise hoga
yeah cuz we cant get an affected female with an unaffected dad
Hmm hmm
Fir to answer hi galat hai
Dekho
Probabilities don’t work like that
Saare independent events hain
Har ek ki roughly similar si probability hai
Completely chance event
independent hai tabhi to bolri
ki bhyi it could bhi anything
dono me hamari possiblity ideal se alag hai ye thoda mujhe hjam nhi hora
Alag hona is very normal
You never get 50 50 na
ik par dono time?
Dono time matlab?
i dont have a feeling ki bhyi isme aisa hona
f1 and f2 both are off of bhyi ki jo usually hota
That is completely normal yes
That too because dono independent hain
Jo bhi possible combinations honge
Roughly sabki same si probability hai
Jyada difference nahi hai
Isiliye pedigree me hume ideal ki bajaye koi or dikhne ka chance jyada hai
Just because hamara sample size chhota hai
par yaha kaha same hai
yaha to dekho na
Combinations ki baat kar raha bua ji
Not particular individual
acha ruko mai combination ke hisab apko karke bhejri
Hua ji?
😃
bua ji se nhi hua ji
raat ko dekhungi abhi lec hai
Bua ji DP dhoondhne gayi thi 🗣️
(Sorry not ruining the thread aage last bas)