When to Use `.pipe()` vs `Effect.gen()` in Effect Typescript

I am trying to figure out when to use

.pipe()

.pipe()

and

Effect.gen()

Effect.gen()

and it seems like anything you could do with

Effect.gen

Effect.gen

you can do with

pipe

pipe

. In the docs I found this which seems like it recommends doing

Effect.gen()

Effect.gen()

Effect Documentation

Simplify nested code with Do simulation and generators.