Is there a way to reset / refresh Proton?

To start off with I mostly use Proton through Steam though this issue affects the Heroic Launcher as well.

When playing some games using Proton after a few days Chromium based applications go wonky and then eventually don't open at all. This includes Steam trying to refresh the store page on a constant loop, Brave opening and then crashing immediately. Eventually I'm unable to launch anything Chromium based which has included Brave Browser, Discord, Steam, The Heroic Launcher, etc.

I was wondering if there are some caches I could clear or some way to reset whatever has messed things up. Restarting the computer does work.

Thank you so much for your time and help!
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