Does Prime Blob adjust for Nozzle Size?

I started to experiment with a .8mm nozzle; never used one that large before. One thing I noticed is that the Prime Blob does not seem to be as large as when using a .4mm nozzle and as such is not as effective in removing "strings" from the nozzle tip. Does anyone know if the nozzle size has an impact on extrusion rate or amount?