motamman - When using an I2C multiplexor, how d...

When using an I2C multiplexor, how do the pull up resistors affect the board? The microcontroller? I am connecting 8 INA260s to a TCA9548A multiplexor to an ESP32-C6. Individually, the INA260s work as expected but when all installed, they are a bit flaky.

Is there a rule of thumb for calculating the total pull-up resistance threshold for a system?
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