Respiration

It says 'of isocitrate', so why do they consider the decarboxylation of alpha-ketoglutaric acid, just because it comes after isocitrate? Most the coaching answer keys say it's option B, but I checked the official key and it's option C. Sometimes I have trouble understanding NTA's brand of logic. Should we apply this understanding of the term to future questions?
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21 Replies
iTeachChem Helper
iTeachChem Helper•5mo ago
@Sheldon J. Plankton
iTeachChem Helper
iTeachChem Helper•5mo ago
Note for OP
+solved @user1 @user2... to close the thread when your doubt is solved. Mention the users who helped you solve the doubt. This will be added to their stats.
Sephrina
Sephrina•5mo ago
actually thers one more step to it in the cycle
Sephrina
Sephrina•5mo ago
where alpha-ketogluteric acid goes for oxidative decarboxylation also
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Sephrina
Sephrina•5mo ago
in our ncert this one is given
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Sephrina
Sephrina•5mo ago
with no proper mention of isocitric acid so it taking in considertaion from citric acid to succinic acid and all the no. of decarboxylation there thts why it is 2 as the ans not one @Emperor Someone nta's logic is broken i agree myself
727
727•5mo ago
Yooo those are some nice notes can you please send them 🥺 The ones for pathways Like if you have one for all
Sephrina
Sephrina•5mo ago
yep ill dm yeah i do these are my notes
Emperor Someone
Emperor SomeoneOP•5mo ago
ye ik that step- but isnt it alpha keto glutaric acid which undergoes decarboxylation? Not isocitrate? how can we say that isocitrate is the one underoing 2 decarboxylations
Sephrina
Sephrina•5mo ago
yeah but see its asking from isocitrate and that is in between citric and aplha keto and ncert doesnt defne that line so we will include tht also
Emperor Someone
Emperor SomeoneOP•5mo ago
mm ok...so just to be clear, if they ask how many times a given compound undergoes decarboxylation, we have to include the decarboxylations which happen in the following steps too, even though it is not the original compound which actually loses the CO2?
Sephrina
Sephrina•5mo ago
just try to compare the diagram from ncert and the process expanded and then count it out
Emperor Someone
Emperor SomeoneOP•5mo ago
i mean even tho they hvnt included isocitrate in the diagram, they mention it in the writing
Sephrina
Sephrina•5mo ago
yep thts why we know its betwen those both alpha keto and citric but not where exactt
Emperor Someone
Emperor SomeoneOP•5mo ago
what im basically asking is this, if in a cycle, X gets decarboxylated to Y and then later Y gets decarboxylated to Z, then we should consider X as undergoing 2 decarboxylations in a cycle?
727
727•5mo ago
yup
Sephrina
Sephrina•5mo ago
yes
Emperor Someone
Emperor SomeoneOP•5mo ago
tyy
Sephrina
Sephrina•5mo ago
np
Emperor Someone
Emperor SomeoneOP•5mo ago
+solved @Sephs
iTeachChem Helper
iTeachChem Helper•5mo ago
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