Looking for recommendations on Java args for a really, really big modpack

I've managed to create a big modpack, and manage to get ApexHosting's EX Series plan for hosting, but what would be the best Java args I can throw at it, on top of optimization mods?

Although tweaks to existing optimization mods are welcome, if you can recommend any, as this is a very massive pack, although Fabric/Quilt likes to be... deceptive with numbers, so the actual jar count is around 600+ mods (I'm working on trimming some fat as I see fit, though.)
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