> If I create a new drizzle instance with a huge schema for each Connection they are going to be kep

If I create a new drizzle instance with a huge schema for each Connection they are going to be kept in memory too.
Sure, but the GC collector will be run more often if you're near the memory limit, so theoretically you'd see those connections being cleaned up more frequently if they were an issue. But I expect they're super lightweight anyway if the connection itself is closed.
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