Using postgres.js direct I can connect but with Hyperdrive, no way.

const runQ = async q => {
    const client = new Client(/* options */);
    await client.connect();
    return client.query(q);
}

const runQ = async q => {
    const client = new Client(/* options */);
    await client.connect();
    return client.query(q);
}

const runQ = async (req, q) => {
    if (!req.client) {
        req.client = new Client(/* options */);
        await req.client.connect();
    }
    return req.client.query(q);
}

const runQ = async (req, q) => {
    if (!req.client) {
        req.client = new Client(/* options */);
        await req.client.connect();
    }
    return req.client.query(q);
}